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RECRUITMENT DOMAINS, CASPASE
Descriptors Found:
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DeCS
Descriptor
English
:
Caspase Activation and Recruitment Domain
Descriptor
Spanish
:
Dominio de Reclutamiento y Activación de Caspasas
Descriptor
Portuguese
:
Domínio de Ativação e Recrutamento de Caspases
Synonyms
English
:
CARD Domain
CARD Domains
Caspase Activation and Recruitment Domains
Caspase Recruitment Domain
Caspase Recruitment Domains
Recruitment Domain, Caspase
Recruitment Domains, Caspase
Tree Number:
G02.111.570.820.709.275.750.500.395.250
Definition
English
:
A homotypic protein interaction module of the
death domain superfamily
. It is composed of a bundle of six alpha-helices that is related in sequence and structure to the
DEATH DOMAIN
and
DEATH EFFECTOR DOMAIN
. The
Caspase Activation and Recruitment Domain
(CARD domain) typically associates with other CARD-containing
proteins
, forming either dimers or trimers. CARD domains may occur in isolation, or in combination with other domains in
CARD signaling adaptor proteins
and
initiator CASPASES
that function in
APOPTOSIS.
See Related
English
:
CARD Signaling Adaptor Proteins
History Note
English
:
2017
Allowable Qualifiers
English
:
DE
drug effects
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects
Record Number:
56746
Unique Identifier:
D000071476
Occurrence in VHL
:
Similar:
DeCS